crebanine Chemical Properties

Melting point:

126 °C

Boiling point:

488.2±45.0 °C(Predicted)

Density 

1.266±0.06 g/cm3(Predicted)

storage temp. 

4°C, protect from light

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Cryst.

pka

6?+-.0.20(Predicted)

color 

Off-white to light yellow

Safety Information

Toxicity

mouse,LD50,intraperitoneal,24230ug/kg (24.23mg/kg),BEHAVIORAL: IRRITABILITYBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDLUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION,Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 20, Pg. 422, 1989.

crebanine Usage And Synthesis

Uses

Crebanine is an aporphine alkaloid which helps sensitize TNF-α induced apoptosis and suppress human lung adenocarcinoma. Known to exhibit anticancer properties.

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