fumagillol
fumagillol Basic information
- Product Name:
- fumagillol
- Synonyms:
-
- 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-, (3R,4S,5S,6R)-
- Fumagillol,Bacterial,inhibit,Inhibitor
- (3R,4S,5S,6R)-5-Methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-ol
- CAS:
- 108102-51-8
- MF:
- C16H26O4
- MW:
- 282.38
- Product Categories:
-
- Aliphatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File:
- 108102-51-8.mol
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fumagillol Chemical Properties
- Melting point:
- 54-56 °C(Solv: ligroine (8032-32-4))
- Boiling point:
- 140 °C(Press: 0.02 Torr)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 100 mg/mL (354.13 mM; Need ultrasonic)
- form
- Solid
- pka
- 14.21±0.60(Predicted)
- color
- White to Off-White
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fumagillol Usage And Synthesis
Uses
Fumagillol is an analog of Fumagillin (F862650), a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-infective and antiangiogenic agent.
Definition
ChEBI: Fumagillol is a sesquiterpenoid with antimicrobial properties. It has a role as an antimicrobial agent. It is a spiro-epoxide, a secondary alcohol and a sesquiterpenoid.
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