demethylwedelolactone Chemical Properties

Melting point:

>360 °C

Boiling point:

531.4±35.0 °C(Predicted)

Density 

1.827±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

powder

pka

7.07±0.20(Predicted)

color 

Yellow

demethylwedelolactone Usage And Synthesis

Uses

1,3,8,9-Tetrahydroxy-6H-benzofuro[3,2-c][1]benzopyran-6-one has anti-cancer properties and inhibits the anchorage-independent growth and suppressed cell motility and cell invasion of MDA-MB-231.

Definition

ChEBI: Demethylwedelolactone is a member of coumestans.

Biological Activity

Demethylwedelolactone is a coumestan extracted from Eclipta alba th at exhibits numerous biological activities including anti-inflammatory and hepato-protective. Demethylwedelolactone inhibits MDA-MB-231 breast cancer cells motility and invasiveness. It suppresses the metastasis and lung colonization of the tumor cells in the nude mice. Both demethylwedelolactone and wedelolactone appear to attenuate cigarette smoking extract induced inflammation through blockade of autophagy flux in respiratory epithelial cells.

demethylwedelolactone(6468-55-9)Related Product Information

• Betaine
• Polycaprolactone
• Isoalantolactone
• polygalaxanthone III
• Cryptochlorogenic acid
• Isochlorogenic acid A
• Isofraxidin
• Isochlorogenic Acid B
• Isocorynoxeine
• Alisol B acetate
• Ginkgolide A
• Polygalacic acid
• NARIRUTIN
• Leonurine hydrochloride
• Nicotinic acid
• WEDELOLACTONE
• COUMESTROL
• demethylwedelolactone