TRANS-7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE CAS#: 57404-88-3

TRANS-7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE Basic information

Product Name:

TRANS-7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE

Synonyms:

TRANS-7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE
Benzo[a]pyrene-7,8-diol, 7,8-dihydro-, (7R,8R)-rel-
trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (>90%)
Benzo(a)pyrene, 7,8-dihydro-7,8-dihydroxy-, (E)-

CAS:

57404-88-3

MF:

C20H14O2

MW:

286.32

Product Categories:

Aromatics, Heterocycles, Mutagenesis Research Chemicals

Mol File:

57404-88-3.mol

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TRANS-7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE Chemical Properties

Boiling point:: 388.69°C (rough estimate)
Density: 1.1197 (rough estimate)
refractive index: 1.7580 (estimate)
solubility: DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated)
form: Solid
color: Light Grey to Dark Grey

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TRANS-7,8-DIHYDROXY-7,8-DIHYDRO-BENZO(A)PYRENE Usage And Synthesis

Uses

trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene is a metabolite of Benzopyrene (B205800). Benzo[a]pyrene (B205800), a prototypic PAH, is metabolized by cytochrome P 450 1A1/1B1. (-)-trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280) undergoes further P 4501A1/1B1-mediated metabolism to a carcinogen, which forms DNA-adducts primarily with 2'-deoxyguanosine. A carcinogen.

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