Dimethyl itaconate Chemical Properties

Melting point:

37-41 °C (lit.)

Boiling point:

208 °C (lit.)

Density 

1.124 g/mL at 25 °C (lit.)

vapor pressure 

4.05Pa at 20℃

refractive index 

1.4457 (estimate)

Flash point:

213 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Crystalline Low Melting Mass or Liquid

Specific Gravity

1.124

color 

White

Water Solubility 

slightly soluble

BRN 

386674

InChIKey

ZWWQRMFIZFPUAA-UHFFFAOYSA-N

LogP

0.86 at 25℃

CAS DataBase Reference

617-52-7(CAS DataBase Reference)

NIST Chemistry Reference

Butanedioic acid, methylene-, dimethyl ester(617-52-7)

EPA Substance Registry System

Butanedioic acid, 2-methylene-, 1,4-dimethyl ester (617-52-7)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

F 

3

HS Code 

29171900

MSDS

• Language:English Provider:Dimethyl itaconate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Dimethyl itaconate Usage And Synthesis

Chemical Properties

white crystalline low melting mass or liquid

Uses

Dimethyl Itaconate is a chemical reagent used in the synthesis of functionalized 2-isoxazolines used in fragment-based drug discovery.

Uses

Dimethyl itaconate may be used in functionalization of isotactic poly(propylene). It was used in crosslinking of polyesters: poly(isosorbide itaconate)and poly(isosorbide itaconate-co-succinate).

Uses

Dimethyl itaconate can be used for the rhodium catalyzed asymmetric hydrogenation of (S)-dimethyl-2-methylsuccinate and (R)-methyl succinic acid dimethyl ester.

General Description

Dimethyl itaconate undergoes enantioselective Rh(I)-catalyzed hydrogenation which can be enhanced by appropriate choice of substituents on aromatic ring of (1,2-diarylphosphinoxy)cyclohexane.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise the ester from MeOH by cooling to -78o. [Beilstein 2 IV 2229.]

Dimethyl itaconate(617-52-7)Related Product Information

• Dimethyl carbonate
• ETHANE
• Dimethyl adipate
• Dimethyl malonate
• Dimethyl fumarate
• Dimethyl phthalate
• Dimethyl sulfate
• Itaconic acid
• Dacthal
• N,N-Dimethylformamide
• Dimethyl ether
• Dimethyl sulfoxide
• Dimethyl phosphite
• Dimethyl sebacate
• Dimethyl oxalate
• Dimethyl sulfide
• DIETHYL ITACONATE
• DIBUTYL ITACONATE