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3,5,4''-TRIHYDROXY-7-METHOXYFLAVONE

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3,5,4''-TRIHYDROXY-7-METHOXYFLAVONE Basic information

Product Name:
3,5,4''-TRIHYDROXY-7-METHOXYFLAVONE
Synonyms:
  • 4H-1-Benzopyran-4-one, 3,5-dihydroxy-2-(4-hydroxyphenyl)-7-methoxy-
  • 7-Methylkaempferol
  • Kaempferol 7-methyl ether
  • Indoctrination
  • astragalus,flavonoid,inhibit,anti-inflammatory,Rhamnocitrin,Inhibitor,complanatus,an-tiatherosclerosis,anti-oxidant,DPPH
  • 3,5,4''-TRIHYDROXY-7-METHOXYFLAVONE
  • 3,4',5-Trihydroxy 7-methoxyflavone
  • Rhamnocitrin-RM
CAS:
569-92-6
MF:
C16H12O6
MW:
300.26
Product Categories:
  • Flavanols
Mol File:
569-92-6.mol
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3,5,4''-TRIHYDROXY-7-METHOXYFLAVONE Chemical Properties

Melting point:
225-227℃
Boiling point:
571.9±50.0 °C(Predicted)
Density 
1.538
storage temp. 
2-8°C
solubility 
Soluble in methan
form 
powder
pka
6.18±0.40(Predicted)
color 
Yellow
InChI
InChI=1S/C16H12O6/c1-21-10-6-11(18)13-12(7-10)22-16(15(20)14(13)19)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3
InChIKey
MQSZRBPYXNEFHF-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(O)C=C2)OC2=CC(OC)=CC(O)=C2C(=O)C=1O
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3,5,4''-TRIHYDROXY-7-METHOXYFLAVONE Usage And Synthesis

Uses

food and beverages

Definition

ChEBI: A monomethoxyflavone that is the 7-methyl ether derivative of kaempferol.

in vivo

After oral administration of A. complanatus extract (10 mL/kg) to rats (equivalent to 17.6 mg/kg Rhamnocitrin), blood (approximately 0.3 mL) is collected from the ocular vein for analysis at 0, 0.083, 0.167, 0.25, 0.333, 0.5, 0.75, 1, 2, 4, 6, 9, and 12 hours after administration under ether anesthesia. The results shows that the plasma concentration of Rhamnocitrin reached its maximum at 0.65 hours, with an average Cmax of 29.57 ng/mL[1].

target

HO-1 | ERK | MEK | p38MAPK | Immunology & Inflammation related

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