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HYODEOXYCHOLIC ACID SODIUM SALT

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HYODEOXYCHOLIC ACID SODIUM SALT Basic information

Product Name:
HYODEOXYCHOLIC ACID SODIUM SALT
Synonyms:
  • SODIUM HYODEOXYCHOLATE
  • 3ALPHA,6ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID SODIUM SALT
  • 5BETA-CHOLAN-24-OIC ACID-3ALPHA,6ALPHA-DIOL SODIUM SALT
  • 3,6-dihydroxy-,monosodiumsalt,(3alpha,5beta,6alpha)-cholan-24-oicaci
  • hyodeoxycholic acid sodium
  • 3α,6α-Dihydroxy-5β-cholan-24-oic acid, Hyodeoxycholic acid sodium salt
  • 3α,6α-Dihydroxy-5β-cholan-24-oic acid sodium salt
  • Sodium 3α,6α-dihydroxy-5β-cholan-24-oate
CAS:
10421-49-5
MF:
C24H39NaO4
MW:
414.55
EINECS:
1806241-263-5
Product Categories:
  • Bile Acids
  • Biochemistry
  • Steroids
Mol File:
10421-49-5.mol
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HYODEOXYCHOLIC ACID SODIUM SALT Chemical Properties

refractive index 
3.5 ° (C=2, H2O)
Water Solubility 
Sparingly soluble in water.(0.26 g/L) (25°C),
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
26-37
HS Code 
29189900
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HYODEOXYCHOLIC ACID SODIUM SALT Usage And Synthesis

Chemical Properties

White to almost white powder

Uses

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor.

in vivo

Hyodeoxycholic acid (HDCA; 1.25% (wt/wt)) sodium obviously decreases fat mass and increases lean mass but does not raise the serum levels of any organ toxicity markers in LDLRKO mice. Hyodeoxycholic acid inhibits atherosclerotic lesion formation in LDLRKO at multiple sites, improves plasma lipoprotein profiles, decreases plasma glucose level and intestinal cholesterol absorption efficiency and increases daily cholesterol excretion through fecal output. Hyodeoxycholic acid sodium also improves HDL function as measured by a cholesterol efflux assay[2].

IC 50

Microbial Metabolite; Human Endogenous Metabolite

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