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6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic acid

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6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic acid Basic information

Product Name:
6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic acid
Synonyms:
  • 6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic acid
  • 6-HYDROXY-2-(METHYLTHIO)-4-PYRIMIDINECARBOXYLIC ACID
  • 6-Hydroxy-2-(methylthio)pyrimidine-4-carboxylic acid
  • 2-(methylsulfanyl)-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid
  • 2-(methylthio)-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid
  • 2-(Methylthio)-6-oxo-3,6-dihydropyrimidine-4-carboxylic acid
  • 4-Pyrimidinecarboxylic acid, 1,6-dihydro-2-(methylthio)-6-oxo-
  • 6-Hydroxy-2-(Methylsulfanyl)-4-Pyrimidinecarboxylic
CAS:
6314-14-3
MF:
C6H6N2O3S
MW:
186.19
Product Categories:
  • pharmacetical
Mol File:
6314-14-3.mol
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Safety Information

HazardClass 
IRRITANT
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6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic acid Usage And Synthesis

Uses

6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic Acid has shown binding to HCR-13pf of MMP-13 hemopexin domain with no crossreactivity to MMP-1 and 8 which could serve as building block for development of drug for osteoarthritis (OA) and rheumatoid arthritis (RA). It can be useful in the structure-??activity relationship studies of pyrimidine base analogs as ligands of orotate phosphoribosyltransferase as well as allosteric inhibitors of a mammalian lectin.

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