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Betaxolol hydrochloride

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Betaxolol hydrochloride Basic information

Product Name:
Betaxolol hydrochloride
Synonyms:
  • 1-[4-[2-(CYCLOPROPYLMETHOXY)ETHYL]PHENOXY]-3-ISOPROPYLAMINO-2-PROPANOL HYDROCHLORIDE
  • BETAXOLOL CHLOROHYDRATE
  • BETAXOLOL HCL
  • BETAXOLOL HYDROCHLORIDE
  • BETAXOLOL HYDROCHLORIDE MONOHYDRATE
  • SL 75212
  • (+-)-1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)-2-propano
  • 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-isopropylaminopropan-2-olhydroc
CAS:
63659-19-8
MF:
C18H30ClNO3
MW:
343.89
EINECS:
264-384-3
Product Categories:
  • Cardiovascular
  • Adrenoceptor
Mol File:
63659-19-8.mol
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Betaxolol hydrochloride Chemical Properties

Melting point:
116°
storage temp. 
2-8°C
solubility 
H2O: 36 mg/mL, soluble
form 
solid
color 
white
Water Solubility 
Soluble to 50 mM in water
Merck 
14,1182
Stability:
Hygroscopic
CAS DataBase Reference
63659-19-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
UA9823000
HS Code 
2922504500
Toxicity
LD50 in mice (mg/kg): 944 orally; 37 i.v. (Manoury)

MSDS

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Betaxolol hydrochloride Usage And Synthesis

Description

Betaxolol hydrochloride is a cardioselective β-adrenergic blocker, reportedly devoid of intrinsic sympathomimetic and membrane stabilizing properties. Its long duration of action permits once-daily dosing in mild to moderate hypertension. It is also being evaluated in glaucoma.

Description

Betaxolol (hydrochloride) (Item No. 26285) is an analytical reference standard categorized as a β1-adrenergic receptor antagonist. Formulations containing β-adrenergic receptor antagonists have been used to enhance physical performance in athletes. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .

Chemical Properties

White or almost white, crystalline powder.

Originator

Synthelabo (France)

Uses

Betaxolol Hydrochloride, a cardioselective β1-adrenergic blocker. An antihypertensive; antiglaucoma.

Uses

antifungal

Definition

ChEBI: The hydrochloride salt of betaxolol.

brand name

Betoptic (Alcon); Kerlone (Sanofi Aventis).

Biological Activity

Selective β 1 -adrenoceptor antagonist.

storage

Store at RT

Betaxolol hydrochlorideSupplier

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