1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine Chemical Properties

Melting point:

139 °C

Boiling point:

300.0±42.0 °C(Predicted)

Density 

1.523±0.06 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

Acetonitrile (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

pka

7.50±0.43(Predicted)

form 

Solid

color 

White to Off-White

InChI

InChI=1S/C4H4ClF3N2O2/c5-1-2(11)9-10-3(12)4(6,7)8/h1H2,(H,9,11)(H,10,12)

InChIKey

DYKIVKLXFDNBMY-UHFFFAOYSA-N

SMILES

C(NNC(CCl)=O)(=O)C(F)(F)F

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

WGK Germany 

WGK 3

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2

1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine Usage And Synthesis

Chemical Properties

White Solid

Uses

Sitagliptin intermediate.

1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine(762240-99-3)Related Product Information

• Sitagliptin Impurity 28
• Sitagliptin Impurity 14
• Sitagliptin Defuoro IMpurity 5
• Sitagliptin DeaMino IMpurity 1
• (S)-Sitagliptin Phosphate
• 2,2,2-TRIFLUORO-N'-(TRIFLUOROACETYL)ACETOHYDRAZIDE
• Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
• Sitagliptin
• Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)-
• (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate
• 2,4,5-TRIFLUOROBENZYL CHLORIDE
• Sitagliptin Impurity 34
• 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE
• ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
• Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate
• Sitagliptin impurity 5
• Sitagliptin Impurity 77
• Sitagliptin Impurity 46