Diethyl chlorophosphate Chemical Properties

Melting point:

95-96 °C

Boiling point:

60 °C2 mm Hg(lit.)

Density 

1.194 g/mL at 25 °C(lit.)

vapor density 

5.94 (vs air)

vapor pressure 

0.1 mm Hg ( 25 °C)

refractive index 

n20/D 1.416(lit.)

Flash point:

142 °F

storage temp. 

2-8°C

solubility 

Chloroform (Sparingly)

form 

Liquid

color 

Clear colorless to light yellow

Water Solubility 

Soluble in alcohol and chloroform. Slightly soluble in water.

Sensitive 

Moisture Sensitive

BRN 

471433

Stability:

Hygroscopic, Moisture Sensitive

InChIKey

LGTLXDJOAJDFLR-UHFFFAOYSA-N

LogP

0.61

CAS DataBase Reference

814-49-3(CAS DataBase Reference)

NIST Chemistry Reference

Phosphorochloridic acid, diethyl ester(814-49-3)

EPA Substance Registry System

Diethyl chlorophosphate (814-49-3)

Safety Information

Hazard Codes 

T+

Risk Statements 

23-27/28-33-26/27/28-34

Safety Statements 

26-36/37/39-45-38-28A-7/9-28

RIDADR 

UN 2927 6.1/PG 1

WGK Germany 

3

RTECS 

TD1400000

F 

10-19-21

TSCA 

Yes

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29199000

Hazardous Substances Data

814-49-3(Hazardous Substances Data)

MSDS

• Language:English Provider:Phosphorochloridic acid diethyl ester
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Diethyl chlorophosphate Usage And Synthesis

Description

Diethyl chlorophosphate is a combustible,clear liquid with an unpleasant odor. Molecularweight=172.76; Boiling point=60℃ at 2.0 mmHg; 81℃at 6.0 mmHg. Freezing/Melting point=0℃. HazardIdentification (based on NFPA-704 M Rating System):Health 4, Flammability 2, Reactivity 2 . Reacts withwater.

Chemical Properties

clear colorless to light yellow liquid

Uses

A phosphorous halide used for biochemical research. Also used as an intermediate in organic synthesis.

General Description

Clear liquid. Diethyl chlorophosphate is used as an intermediate in organic synthesis.

Reactivity Profile

Organophosphates, such as Diethyl chlorophosphate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Health Hazard

Diethyl chlorophosphate is a cholinesterase inhibitor. It has high oral and very high dermal toxicity. It is a skin irritant. It is also toxic by inhalation.

Fire Hazard

Emits very toxic fumes of chloride and phosphorus oxides when heated to decomposition.

Safety Profile

Deadly poison by skin contact. Poison by ingestion. A cholinesterase inhibitor. See also PARATHION. Trace HCl catalyzes a hazardous reaction during the preparation of diethyl phosphate from diethyl chlorophosphate. When heated to decomposition it emits very toxic fumes of Cl and POx.

Potential Exposure

This material may be used as an intermediate in the manufacture of pesticides and chemical warfare agents.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Speed in removing material from skinis of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If thischemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, includingresuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give conscious victims water or milk.Promote excretion by administering saline cathartic or sorbitol. Do not make an unconscious person vomit.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from oxidizers and reducing agents.Where possible, automatically pump liquid from drums orother storage containers to process containers.

Shipping

Organophosphorus compound, toxic n.o.s.requires a label of “POISONOUS/TOXIC MATERIALS.”These materials fall in Hazard Class 6.1 and Packing GroupII.

Incompatibilities

Contact with oxidizers may cause therelease of phosphorous oxides. Contact with strong reducingagents, such as hydrides, may cause the formation of flammable and toxic phosphine gas. Strong oxidizers, bases.

Diethyl chlorophosphate(814-49-3)Related Product Information

• Diphenyl chlorophosphate
• Mefenpyr-diethyl
• Diethylphosphorodithioate
• Ethyl dichlorophosphate
• Diethyl methylphosphonate
• DIETHYL PHOSPHATE
• Diethyl carbonate
• Diethyl cyanomethylphosphonate
• Triethyl phosphite
• DIETHYL ETHYLPHOSPHONATE
• Diethyl phthalate
• Diethyl cyanophosphonate
• Clodronate disodium
• Triethyl phosphate
• Diethyl phosphite
• Methyl acrylate
• Diethyl malonate
• Tris(trimethylsilyl)phosphate