Acetylferrocene Chemical Properties

Melting point:

81-83 °C (lit.)

Boiling point:

160-163 °C (3.0004 mmHg)

Density 

>1 g/cm3 (20℃)

Flash point:

160-163°C/4mm

storage temp. 

Sealed in dry,Room Temperature

form 

Needle-Like Crystalline Powder

color 

Orange

Water Solubility 

insoluble

Exposure limits

ACGIH: TWA 1 mg/m3
NIOSH: TWA 1 mg/m3

Stability:

Stable. Incompatible with strong oxidizing agents, reducing agents, strong acids, strong bases.

CAS DataBase Reference

1271-55-2(CAS DataBase Reference)

NIST Chemistry Reference

Acetylferrocene(1271-55-2)

EPA Substance Registry System

Ferrocene, acetyl- (1271-55-2)

Safety Information

Hazard Codes 

T+

Risk Statements 

28

Safety Statements 

28-36/37-45-28A-1

RIDADR 

UN 2811 6.1/PG 2

WGK Germany 

3

RTECS 

OB3700000

F 

10

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29310095

Toxicity

LDLo orl-rat: 5 mg/kg EPASR* 8EHQ-1285-0578

MSDS

• Language:English Provider:(Acetylcyclopentadienyl)cyclopentadienyliron
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Acetylferrocene Usage And Synthesis

Chemical Properties

orange crystalline powder

Uses

1-Acetylferrocene was originally used in military or space field as an additive in rocket propellant, to promote the burning rate. Its ferrocenyl derivative has wide applications to biological and medical fields such as ferrocene-modified beta-lactam because of its physiological activity of anti-malarial, anti-tumor, bactericidal, anti-inflammatory, treatment of anemia, inhibition of enzymatic activity and so on by virtue of its unique structure and diverse properties.

Safety Profile

Poison by ocular and intravenous routes. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes.

Purification Methods

Orange-red crystals are obtained when it is recrystallised from isooctane or *C6H6, and then sublimed at 100o/1mm. The oxime has m 167-170o (from Et2O or aqueous EtOH). The semicarbazone has m 198-201o (from EtOH). [Richmond & Freiser J Am Chem Soc 77 2022 1955, Weinmayer J Am Chem Soc 77 3009 1955, Broadhead et al. J Chem Soc 650 1958, Beilstein 16 IV 1798.]

Acetylferrocene(1271-55-2)Related Product Information

• Aminoferrocene
• Ethylferrocene
• Vinylferrocene
• tert-Butylferrocene
• Ferrocene
• ETHYNYLFERROCENE
• Ferrocenecarboxylic acid
• Ferrocenecarboxaldehyde
• 4'-Methoxyacetoacetanilide
• ACETYLPHOSPHONIC ACID DIETHYL ESTER
• Diethyl acetylmalonate
• 1,1'-Diacetylferrocene
• 1,1'-DIBENZOYLFERROCENE
• 3-FERROCENOYLPROPIONIC ACID
• Benzoylferrocene
• 1,3-Cyclopentadiene
• Butyrylferrocene
• Propionylferrocene