2-Naphthalenesulfonyl chloride Chemical Properties

Melting point:

74-76 °C (lit.)

Boiling point:

147.7 °C/0.6 mmHg (lit.)

Density 

1.3661 (estimate)

vapor pressure 

0.004Pa at 25℃

Flash point:

200-202°C/13mm

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

soluble in Toluene

form 

Powder

color 

Light yellow to beige

Water Solubility 

insoluble

Sensitive 

Moisture Sensitive

BRN 

641898

InChIKey

OPECTNGATDYLSS-UHFFFAOYSA-N

LogP

2.2 at 25℃

CAS DataBase Reference

93-11-8(CAS DataBase Reference)

NIST Chemistry Reference

2-Naphthalenesulfonyl chloride(93-11-8)

EPA Substance Registry System

2-Naphthalenesulfonyl chloride (93-11-8)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45-27

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

21

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29049020

MSDS

• Language:English Provider:2-Naphthalenesulfonyl chloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
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2-Naphthalenesulfonyl chloride Usage And Synthesis

Chemical Properties

LIGHT YELLOW TO BEIGE POWDER

Uses

2-Naphthalenesulfonyl chloride was employed as capping reagent for primary amine to convert histamine to a selective histamine H₃-receptor antagonist. It was used for pre-column derivatization during the high-performance liquid chromatographic assay of neomycin sulfate.

Flammability and Explosibility

Not classified

Purification Methods

Distil the chloride in a vacuum and/or recrystallise it (twice) from *benzene/pet ether (1:1 v/v). Purify it as the 1-sulfonyl chloride above. [Fierz-Davaid & Weissenbach Helv Chim Acta 3 2312 1920.] The sulfonamide has m 217o (from EtOH). [Beilstein 11 III 399, 11 IV 529.]

2-Naphthalenesulfonyl chloride(93-11-8)Related Product Information

• N-Acetylsulfanilyl chloride
• Choline chloride
• Sodium chloride
• Ammonium chloride
• 4-Nitrobenzenesulfonyl chloride
• Benzenesulfonyl chloride
• Benzyl chloride
• Calcium chloride
• Tosyl chloride
• Sulfuryl chloride
• Mepiquat chloride
• Polyvinyl chloride
• 1-NAPHTHALENESULFONYL CHLORIDE,alpha-Naphthalenesulfonyl chloride
• Methanesulfonyl chloride
• Methylene Chloride
• 2-Chloro-6-naphthalenesulfonyl chloride
• Dansyl chloride
• 2-ANTHRACENESULFONYL CHLORIDE