STRYCHNINE Chemical Properties

Melting point:

284-286 °C(lit.)

Density 

1.0926 (rough estimate)

refractive index 

1.6000 (estimate)

solubility 

chloroform: clear to hazy

pka

8.26(at 25℃)

Merck 

8855

CAS DataBase Reference

60-41-3(CAS DataBase Reference)

EPA Substance Registry System

Strychnine sulfate (60-41-3)

Safety Information

Hazard Codes 

T+,N

Risk Statements 

27/28-50/53-26/28

Safety Statements 

36/37-45-60-61-28-13

RIDADR 

UN 1692 6.1/PG 1

WGK Germany 

3

RTECS 

WL2550000

HazardClass 

6.1(a)

PackingGroup 

I

Toxicity

LD50 orally in rats: 5 mg/kg, E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972)

MSDS

• Language:English Provider:SigmaAldrich

STRYCHNINE Usage And Synthesis

Chemical Properties

Strychnine is a colorless crystalline prisms or white powder. It is odorless; with a bitter taste

Uses

central stimulant

Uses

Chiefly in poison baits for rodents.

General Description

Colorless, odorless, very bitter crystals or white crystalline powder. Has been used as a tonic and stimulant in veterinary medicine. Registered as a rodenticide in the U.S.

Reactivity Profile

STRYCHNINE is an alkaloid derivative. STRYCHNINE is a base and forms water soluble salts with acids. Avoid alkalis, alkali carbonates and bicarbonates, benzoates, dichromates, bromides, iodides, tannic and picric acids, salicylates, borax, gold chloride and other alkaloid precipitants, piperazine, potassium-mercuric iodide. Protect from light. [EPA, 1998] STRYCHNINE is incompatible with the following: Strong oxidizers .

Health Hazard

Violent poison!. Lowest published lethal dose orally in humans is 30 mg/kg.

Fire Hazard

When heated to decomposition, STRYCHNINE emits very toxic fumes of sulfur oxides and nitrogen oxides. Avoid alkalies, alkali carbonates and bicarbonates, benzoates, dichromates, bromides, iodides, tannic and picric acids, salicylates, borax, gold chloride and other alkaloid precipitants, piperazine, potassium-mercuric iodide. Protect from light.

Safety Profile

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also STRYCHNINE and SULFATES

Potential Exposure

de, requiring a certified applicator. Strychnine is an alkaloid compound that has been widely used as a rodenticide/bait to kill rodents; a medicine, respiratory stimulant. A potential danger to those involved in the extraction the seeds of the Strychnos nux vomica, Strychnos ignatii (S. sancta Ingnatius), and Strychnos tiente (Upas tree); formulation or application of this rodent poison. The sulfate is used to kill gophers and moles. A common adulterant in illicit street drugs. Listed as a potential WMD biotoxin.

Shipping

UN1692 Strychnine or strychnine salts, Hazard Class: 6.1; Labels: 6.1-Poisonous material.

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Dangerous when heated; forms toxic fumes, including nitrogen oxides. In the body, caffeine may increase the strychnine effect.

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treatment, and waste disposal. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Careful incineration has been recommended for disposal. Two procedures are suggested. Pour or sift onto a thick layer of sand and soda ash mixture (90-10). Mix and shovel into a heavy paper box with much paper packing Burn in incinerator. Fire may be augmented by adding excelsior and scrap wood. Stay on the upwind side. Waste may be dissolved in flammable solvent (alcohols, benzene, etc.) and sprayed into fire box of an incinerator with afterburner and scrubber.

STRYCHNINE(60-41-3)Related Product Information

• Strychnine Nitrate
• Dimethoxy strychnine hydrochloride
• STRYCHNINE
• STRYCHNINE SULFATE PENTAHYDRATE
• 2,3-Dimethoxy-strychnine,Dimethoxy strychnine,Strychnine, 2,3-dimethoxy-
• Dimethoxy strychnine sulfate
• strychnine,monohydrochlorid
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• STRYCHNINE, [BENZENE-3H]-,STRYCHNINE, [BENZENE RING-3H]-
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• strychnine,n(sup6)-oxid
• STRYCHNINE N-OXIDE HYDROCHLORIDE
• STRYCHNINE SULFATE, 5-HYDRATE
• STRYCHNINE HYDROCHLORIDE, DIHYDRATE
• STRYCHNINE ARSENATE
• STRYCHNINE SOLUTION 100UG/ML IN METHANOL 5ML
• STRYCHNINE SOLUTION 100UG/ML IN METHANOL 1ML
• STRYCHNINE SOLUTION 100UG/ML IN METHANOL 5X1ML