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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Pyridine compound >  Hydroxypyridine >  2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE

2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE

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2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE Basic information

Product Name:
2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
Synonyms:
  • 2-HYDROXYPYRIDINE-5-BORONIC ACID, PINACOL ESTER
  • 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE
  • 6-HYDROXY-PYRIDINE-3-BORONIC ACID, PINACOL ESTER
  • 6-HYDROXYPYRIDIN-3-YLBORONIC ACID, PINACOL ESTER
  • 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol
  • 5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-pyridinone
  • 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol
  • 6-Hydroxypyridine-3-boronic acid, pinacol ester, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol
CAS:
1054483-78-1
MF:
C11H16BNO3
MW:
221.06
EINECS:
214-589-6
Product Categories:
  • Boronate Esters
  • Boronic Acids and Derivatives
  • Chemical Synthesis
  • Heteroaryl Boronate Esters
  • Organometallic Reagents
Mol File:
Mol File
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2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE Chemical Properties

Melting point:
197-198
Density 
1.10±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
11.98±0.10(Predicted)
form 
solid
color 
White
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38-38-36
Safety Statements 
26-36/37/39
WGK Germany 
2
HS Code 
2933399990
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2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE Usage And Synthesis

Uses

6-Hydroxypyridine-3-boronic acid pinacol ester can be used as a reactant:

  • In the synthesis of novel glutamate transporter EAAT2 activators.
  • To prepare crizotinib derivatives as SHIP2 inhibitors.

Uses

2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE is used in the preparation of modified C3 Betulinic acid (B330250) derivatives as HIV maturation inhibitors.

2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINESupplier

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