Colestipol hydrochloride
Colestipol hydrochloride Basic information
- Product Name:
- Colestipol hydrochloride
- Synonyms:
-
- Colestipol Hydrochloride (200 mg)
- COLESTIPOL HCL
- COLESTIPOL HYDROCHLORIDE
- N-(2-AMINOETHYL)-N'-[2-[(2-AMINOETHYL)AMINO]ETHYL]-1,2-ETHANEDIAMINE POLYMER WITH (CHLOROMETHYL)OXIRANE HYDROCHLORIDE
- n'-(2-aminoethyl)-n-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine 2-(chloromethyl)oxirane hydrochloride
- cholestabyl
- colestid
- lestid
- CAS:
- 37296-80-3
- MF:
- C8H24ClN5
- MW:
- 225.76266
- Mol File:
- 37296-80-3.mol
Colestipol hydrochloride Chemical Properties
- storage temp.
- Room Temperature, under inert atmosphere
- form
- Solid
- color
- Off-White to Pale Yellow
Colestipol hydrochloride Usage And Synthesis
Uses
Antihyperlipidemic.
Uses
Colestipol Hydrochloride was useful for studying pharmacokinetics with Teriflunomide (A771726).
Definition
ChEBI: The hydrochloride of colestipol, a highly cross-linked, high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. It is used for binding bile acids in the intestine, inhibiting their reabsorption.
brand name
Colestid (Pharmacia & Upjohn).
General Description
Colestipol (Colestid) is ahigh–molecular-weight, insoluble, granular copolymer oftetraethylenepentamine and epichlorohydrin. It functions asan anion-exchange, resin-sequestering agent in a manner similarto that of cholestyramine resin. Colestipol hydrochloridereduces cholesterol levels without affecting triglycerides andseems to be especially effective in the treatment of type IIhyperlipoproteinemias.
Drug interactions
Potentially hazardous interactions with other drugs
Anticoagulants: may enhance or reduce effects of
coumarins and phenindione.
Ciclosporin: no reports of an interaction; however,
ciclosporin levels should be carefully monitored if
colestipol and ciclosporin are prescribed concurrently,
as colestipol may interfere with ciclosporin
absorption.
Metabolism
Not applicable as colestipol is not systemically absorbed.
Colestipol hydrochlorideSupplier
- Tel
- 1-(800)-881-8210
- inquiries@lgmpharma.com
- Tel
- 86-21-63210123
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- 010-50973186 4009686088
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- 027-87466105 15377573527
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- +86-0571-85134551
- info@afinechem.com
Colestipol hydrochloride(37296-80-3)Related Product Information
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