2'-O-GALLOYLHYPERIN
2'-O-GALLOYLHYPERIN Basic information
- Product Name:
- 2'-O-GALLOYLHYPERIN
- Synonyms:
-
- 2''-galloylhyperin
- 3 -O-GALLOYLHYPERIN
- Quercetin 3-beta-galactoside-2''-gallate
- Quercetin 3-β-galactoside-2''-gallate
- Quercetin 3-b-galactoside-2'-O-gallate
- -O-GALLOYLHYPERIN
- [6-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl]oxy-2,3-dihydroxy-4-(hydroxymethyl)cyclohexyl] 3,5-dihydroxy-4-methoxybenzoate
- Q-100605
- CAS:
- 53209-27-1
- MF:
- C28H24O16
- MW:
- 616.48
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 53209-27-1.mol
2'-O-GALLOYLHYPERIN Chemical Properties
- Boiling point:
- 1106.9±65.0 °C(Predicted)
- Density
- 1.94±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
- form
- A crystalline solid
- pka
- 6.17±0.40(Predicted)
- color
- Light yellow to yellow
2'-O-GALLOYLHYPERIN Usage And Synthesis
Chemical Properties
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from deer tongue grass and Apocynum venetum.
Uses
2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage[1][2].
Definition
ChEBI: 2''-galloylhyperin is a member of flavonoids and a glycoside.
References
[1] Wang P, et al. 2'-O-Galloylhyperin Isolated From Pyrola incarnata Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo. Front Pharmacol. 2018 Jun 27;9:679. DOI:10.3389/fphar.2018.00679
[2] Wang P, et al. Hepatoprotective effect of 2'-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway. Food Chem Toxicol. 2017 Apr;102:129-142. DOI:10.1016/j.fct.2017.02.016
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