4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE Chemical Properties

storage temp. 

Store at -20°C

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): .5 mg/ml; Ethanol: 20 mg/ml

form 

A crystalline solid

4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE Usage And Synthesis

Description

Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC₅₀ value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.

4-HYDROXYCINNAMIC ACID (L-PHENYLALANINE METHYL ESTER) AMIDE(615264-52-3)Related Product Information

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