2-(tert-Butylamino)ethanol Chemical Properties

Melting point:

41-43 °C(lit.)

Boiling point:

90-92 °C25 mm Hg(lit.)

Density 

0.867 g/mL at 25 °C(lit.)

vapor density 

4 (vs air)

refractive index 

1.4444 (estimate)

Flash point:

156 °F

storage temp. 

Store below +30°C.

form 

low melting solid

pka

14.81±0.10(Predicted)

InChI

InChI=1S/C6H15NO/c1-6(2,3)7-4-5-8/h7-8H,4-5H2,1-3H3

InChIKey

IUXYVKZUDNLISR-UHFFFAOYSA-N

SMILES

C(O)CNC(C)(C)C

CAS DataBase Reference

4620-70-6(CAS DataBase Reference)

EPA Substance Registry System

Ethanol, 2-[(1,1-dimethylethyl)amino]- (4620-70-6)

Safety Information

Hazard Codes 

C

Risk Statements 

21-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2923 8/PG 2

WGK Germany 

3

RTECS 

KK7177500

F 

9

HS Code 

2922 19 00

HazardClass 

8

PackingGroup 

II

Toxicity

LD50 orally in Rabbit: 1620 mg/kg LD50 dermal Rabbit 635 mg/kg

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

2-(tert-Butylamino)ethanol Usage And Synthesis

Chemical Properties

white solid or crystalline needles

Uses

2-(tert-Butylamino)ethanol is used in the catalytic carbonylation of aliphatic amines to beta-lactams.

Hazard

Moderately toxic by ingestion and skin con- tact. A severe eye irritant.

Research

A sterically hindered alkanol amine, 2-(tertbutylamino)ethanol (TBAE), was reported to be able to reversibly interact with CO2 in a 1/1 molar ratio exclusively through its ?OH group, producing zwitterionic carbonate species in 30% ethylene glycol (EG) solution of TBAE but not carbamate or bicarbonate that can be produced by the prototypical amines[1].

References

[1] Hong-Bin Xie. “CO2 Absorption in an Alcoholic Solution of Heavily Hindered Alkanolamine: Reaction Mechanism of 2-(tert-Butylamino)ethanol with CO2 Revisited.” The Journal of Physical Chemistry A 119 24 (2015): 6346–6353.

2-(tert-Butylamino)ethanol(4620-70-6)Related Product Information

• TRT-GLY-OH
• 2-(2-HYDROXYETHYLAMINO)-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL
• N-(TRIPHENYLMETHYL)GLYCINE ETHYL ESTER
• Salbutamol
• Tricine
• 2-(TERT-BUTYLAMINO)ETHANOL
• AMPSO sodium salt
• TERBUTALINE SULFATE
• S-(+)-Albuterol
• TRIFENMORPH
• 2-(TERT-BUTYLAMINO)ETHYL METHACRYLATE
• 1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol hydrochloride
• BIS-Tris
• 3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid sodium salt
• 2-Methyl-4'-(methylthio)-2-morpholinopropiophenone
• NADOLOL
• Butoxamine hydrochloride
• N-TERT-BUTYLDIETHANOLAMINE