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EURYCOMANONE

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EURYCOMANONE Basic information

Product Name:
EURYCOMANONE
Synonyms:
  • EURYCOMANONE
  • 11,2o-epoxy-1,11,12,14,15-pentahydroxy-13(21)-diene-(1-picrasa-16-dione
  • 11-beta,12-alpha,15-beta)-betdihydrate
  • pasakbumin-a
  • 11β,20-Epoxy-1β,11,12α,14,15β-pentahydroxypicrasa-3,13(21)-diene-2,16-dione
  • NSC 339187
  • (1beta,8xi,11beta,12alpha,15beta)-1,11,12,14,15-pentahydroxy-11,20-epoxypicrasa-3,13(21)-diene-2,16-dione
  • Eurycoma longifolia
CAS:
84633-29-4
MF:
C20H24O9
MW:
408.4
Product Categories:
  • Apoptosis, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
84633-29-4.mol
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EURYCOMANONE Chemical Properties

Melting point:
273-285℃ (methanol ethyl ether )
Boiling point:
669.5±55.0 °C(Predicted)
Density 
1.63±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form 
Solid
pka
11.29±0.70(Predicted)
color 
Off-White to Pale Beige
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EURYCOMANONE Usage And Synthesis

Uses

Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.

Definition

ChEBI: A quassinoid isolated from Eurycoma longifolia and has been shown to exhibit antineoplastic and antimalarial activties.

EURYCOMANONESupplier

Changsha Hepu Biological Technology Co. Ltd Gold
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Chengdu Biopurify Phytochemicals Ltd.
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UHN Shanghai Research & Development Co., Ltd.
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