(2S)-(+)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine Chemical Properties

alpha 

102 º (c=1%, EtOH)

Boiling point:

245.2±33.0 °C(Predicted)

Density 

1.028 g/mL at 20 °C (lit.)

storage temp. 

Sealed in dry,2-8°C

solubility 

Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly), Methanol (Slightly)

pka

3.81±0.60(Predicted)

form 

Liquid

color 

Clear colorless to pale yellow

optical activity

[α]20/D +102.0±5°, c = 1% in ethanol

BRN 

3650245

InChI

InChI=1S/C9H16N2O2/c1-6(2)8-9(13-4)10-5-7(11-8)12-3/h6,8H,5H2,1-4H3/t8-/m0/s1

InChIKey

FCFWEOGTZZPCTO-QMMMGPOBSA-N

SMILES

[C@@H]1(C(C)C)N=C(OC)CN=C1OC

CAS DataBase Reference

78342-42-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

23-24/25-37/39-26

WGK Germany 

3

HS Code 

29335995

MSDS

• Language:English Provider:SigmaAldrich

(2S)-(+)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine Usage And Synthesis

Chemical Properties

Clear colorless to pale yellow liquid

Uses

(2S)-(+)-2,5-Dihydro-2-isopropyl-3,6-dimethoxypyrazine is a Sch?llkopf-Hartwig bislactim ether reagent for asymmetric synthesis of amino acids by reaction of the  metalated reagent with alkyl halides, aldehydes, ketones, epoxides, and enones, and subsequent hydrolysis of the resulting bislactim ether adduct.

(2S)-(+)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine(78342-42-4)Related Product Information

• 3-Mercaptopropyltriethoxysilane
• Dihydromyrcenol
• 3-Chloropropyltriethoxysilane
• Dimethyldimethoxysilane
• 2,6-Dimethoxybenzaldehyde
• (R)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• Phenazine methosulfate
• 3-Aminopropyltriethoxysilane
• 1,1-Dimethoxyethane
• Diphenyldimethoxysilane
• Dimethoxymethane
• 2-ISOPROPYLPYRAZINE
• (S)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine
• (2S,5SR)-(+)-2,5-Dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine
• (2S)-(+)-2,5-Dihydro-3,6-dimethoxy-2-isopropylpyrazine
• Dimethoxy
• (2R,5S)-2,5-DIHYDRO-3,6-DIMETHOXY-2-[2',5'-DIFLUOROPHENYL)METHYL]-5-ISOPROPYL-PYRAZINE