4-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZYL]MORPHOLINE Chemical Properties

Melting point:

76-78

Boiling point:

400.8±35.0 °C(Predicted)

Density 

1.08

storage temp. 

Inert atmosphere,Room Temperature

solubility 

soluble in Methanol

form 

powder to crystal

pka

6.49±0.10(Predicted)

color 

White to Almost white

InChI

InChI=1S/C17H26BNO3/c1-16(2)17(3,4)22-18(21-16)15-7-5-14(6-8-15)13-19-9-11-20-12-10-19/h5-8H,9-13H2,1-4H3

InChIKey

JOIXYIWXEYXHHG-UHFFFAOYSA-N

SMILES

N1(CC2=CC=C(B3OC(C)(C)C(C)(C)O3)C=C2)CCOCC1

Safety Information

Hazard Codes 

C

WGK Germany 

3

Hazard Note 

Corrosive

HS Code 

2934999090

4-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZYL]MORPHOLINE Usage And Synthesis

Uses

4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)morpholine is a synthetic chemical that is used in industrial synthesis. It can be used in the production of pharmaceuticals, plastics, pesticides, and herbicides.

Synthesis

4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)morpholine can be synthesized from bromobenzoate and pinacol in high yield under mild reaction conditions.

References

[1] Patent: WO2009/155565, 2009, A1. Location in patent: Page/Page column 143-144
[2] Patent: WO2013/153357, 2013, A1. Location in patent: Page/Page column 18; 39; 40
[3] Patent: US2015/45354, 2015, A1. Location in patent: Paragraph 0237-0241
[4] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 20, p. 2989 - 2992
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 2, p. 196 - 218

4-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZYL]MORPHOLINE(364794-79-6)Related Product Information

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