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(+)-ISOLARICIRESINOL

Basic information Safety Supplier Related

(+)-ISOLARICIRESINOL Basic information

Product Name:
(+)-ISOLARICIRESINOL
Synonyms:
  • -Conidendryl alcohol
  • Isolariciresinol (6CI)
  • (+)-ISOLARICIRESINOL
  • ISOLARICIRESINOL
  • (1S)-1,2,3,4-Tetrahydro-7-hydroxy-1α-(4-hydroxy-3-methoxyphenyl)-6-methoxy-2β,3α-naphthalenedimethanol
  • (1S)-1α-(3-Methoxy-4-hydroxyphenyl)-6-methoxy-7-hydroxy-1,2,3,4-tetrahydronaphthalene-2β,3α-bismethanol
  • (2R)-4β-(4-Hydroxy-3-methoxyphenyl)-6-hydroxy-7-methoxy-1,2,3,4-tetrahydronaphthalene-2β,3α-dimethanol
  • (7S,8R,8'R)-(+)-Cyclolariciresinol
CAS:
548-29-8
MF:
C20H24O6
MW:
360.4
Product Categories:
  • Miscellaneous Natural Products
Mol File:
548-29-8.mol
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(+)-ISOLARICIRESINOL Chemical Properties

Melting point:
112 °C
Boiling point:
584.1±50.0 °C(Predicted)
Density 
1.275±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Acetone: soluble,Chloroform: soluble,Dichloromethane: soluble,DMSO: soluble,Ethyl Acetate: soluble
form 
Powder
pka
10.08±0.35(Predicted)
color 
White to off-white
LogP
1.640 (est)
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(+)-ISOLARICIRESINOL Usage And Synthesis

Uses

Cyclolariciresinol can be used to reduce oxidative stress and inflammation by activating farnesoid x receptor in cholestatis by alpha-naphthylisothiocyanate.

Definition

ChEBI: (+)-isolariciresinol is a lignan that is 5,6,7,8-tetrahydronaphthalen-2-ol substituted by hydroxymethyl groups at positions 6 and 7, a methoxy group at position 3 and a 4-hydroxy-3-methoxyphenyl group at position 8. It has been isolated from the roots of Rubia yunnanensis. It has a role as a plant metabolite. It is a lignan, a polyphenol, a primary alcohol and a member of guaiacols.

target

Immunology & Inflammation related

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