PROSTAGLANDIN B1 Chemical Properties

Melting point:

69-71°C

Boiling point:

531.4±43.0 °C(Predicted)

Density 

1.101±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

acetone: 20 mg/mL, clear, colorless to very faintly yellow

form 

powder

pka

4.77±0.10(Predicted)

color 

white to light yellow

BRN 

2004447

Stability:

Light Sensitive

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

8-10

HS Code 

2937500000

MSDS

• Language:English Provider:SigmaAldrich

PROSTAGLANDIN B1 Usage And Synthesis

Uses

Prostaglandin B1 is a novel microbial biopolymer which has been shown to improve the longevity of type 2 diabetic rodents. Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells.

Definition

ChEBI: Prostaglandin B1 is a member of the class of prostaglandins B that is prosta-8(12),13-dien-1-oic acid carrying oxo and hydroxy substituents at positions 9 and 15 respectively (the 13E,15S-stereoisomer). It has a role as a human metabolite. It is a conjugate acid of a prostaglandin B1(1-).

Enzyme inhibitor

This eicosanoid (FWB1 (free-acid) = 336.47 g/mol; CAS 13345-51-2, for PGB1, and 39306-29-1, for Bx) is a metabolite of prostaglandin E1: prostaglandin Bx is an oligomer of prostaglandin B1. The X-ray crystal structure of prostaglandin B1 suggests this prostaglandin has an unusual L-shaped configuration, with the a and w side chains roughly perpendicular to one another. The 15-hydroxyl group, which is normally directed away from the centroid of the prostaglandin in the standard hairpin mod+el, is turned inward in prostaglandin B1. Target (s) : FoF1 ATPase, or H-transporting two-sector ATPase, inhibited by prostaglandin Bx; 15- hydroxyprostaglandin dehydrogenase; phospholipase A2, inhibited by prostaglandin Bx.

PROSTAGLANDIN B1(13345-51-2)Related Product Information

• Prostaglandin E1
• Prostaglandin E2
• PROSTAGLANDIN A2
• PROSTAGLANDIN B2
• PROSTAGLANDIN A1
• PROSTAGLANDIN B1
• TRANS-2-TRIDECEN-1-OL
• 3-methylcyclopent-2-en-1-one
• 2-PENTYL-2-CYCLOPENTEN-1-ONE
• PROSTAGLANDIN B1
• 1-Methylcyclopentene
• trans,trans-2,4-Nonadienal
• 1-ETHYL-2-METHYLCYCLOPENTENE
• 2-METHYL-2-CYCLOPENTEN-1-ONE
• 2-Cyclopenten-1-one
• 2-Pentyl-3-methyl-2-cyclopenten-1-one
• 2-OCTEN-4-OL
• Fluprostenol