Isophthalic dihydrazide Chemical Properties

Melting point:

224°C

Density 

1.344±0.06 g/cm3(Predicted)

vapor pressure 

0-0Pa at 20-25℃

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

form 

Solid:particulate/powder

pka

11.87±0.10(Predicted)

color 

White to Almost white

LogP

-1.4 at 20℃ and pH7.1

Surface tension

74.4mN/m at 1g/L and 20℃

CAS DataBase Reference

2760-98-7(CAS DataBase Reference)

EPA Substance Registry System

Isophthalic acid dihydrazide (2760-98-7)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HS Code 

29280000

Isophthalic dihydrazide Usage And Synthesis

Synthesis

Isophthalic dihydrazide is prepared by the reaction of Dimethyl isophthalate and Hydrazine hydrate. The specific synthesis steps are as follows:
A mixture of dimethyl ester of isophthalic acid (2.22 gm) and hydrazine hydrate (98percent, 2 cc) in methanol was refluxed for 5 hours and the reaction mixture was allowed to cool to room temperature. Then, the cooled reaction mixture was poured on to ice cold water. The dihydrazide of isophthalic acid thus obtained was filtered and recrystallized from ethanol. [1] Yield: (85percent), M.P=241℃, (Scheme1). 1HNMR (400 MHz, CDCL3, ppm): 9.81 (s, 2H, -CO-NH-), 8.20 (s 1H ), 7.8(d, 2H, J=7.6 Hz), 7.5 (t, 1H, 7.2 Hz), 4.5 (s, 4H).

Isophthalic dihydrazide(2760-98-7)Related Product Information

• Ethyl 2-(Chlorosulfonyl)acetate
• O-Phthalimide
• 2-Benzoylbenzoic acid
• Dimethyl isophthalate
• Adipic dihydrazide
• Isophthalic acid
• Folic acid
• 5-Hydroxyisophthalic acid
• Phthalhydrazide
• Glycine
• 1,5-Diphenylcarbazide
• 1,3-Bis(aminomethyl)benzene
• 1,2-Diformylhydrazine
• Isophthaloyl dichloride
• Methyl benzoylformate
• 1,3-Dicyanobenzene
• TEREPHTHALIC DIHYDRAZIDE
• 5-Aminoisophthalic acid