Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Pyrimidines >  Aminopyrimidine >  5-Amino-4,6-dichloropyrimidine

5-Amino-4,6-dichloropyrimidine

Basic information Safety Supplier Related

5-Amino-4,6-dichloropyrimidine Basic information

Product Name:
5-Amino-4,6-dichloropyrimidine
Synonyms:
  • 4,6-DICHLORO-5-PYRIMIDINAMINE
  • 4,6-DICHLOROPYRIMIDIN-5-AMINE
  • 4,6-DICHLOROPYRIMIDIN-5-YLAMINE
  • AKOS 91433
  • 5-PYRIMIDINAMINE, 4,6-DICHLORO-
  • 4,6-Dichloro-5-aminopyrimidine
  • 4,6-dichloro-5-pyrimidinamin
  • 5-AMINO-4,6-DICHLOROPYFIMIDINE
CAS:
5413-85-4
MF:
C4H3Cl2N3
MW:
163.99
EINECS:
226-503-7
Product Categories:
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Pyrimidine
  • Pyrimidines
  • Heterocyclic Compounds
  • PyrimidinesHeterocyclic Building Blocks
  • Aromatics
  • Heterocycle-Pyrimidine series
  • bc0001
Mol File:
5413-85-4.mol
More
Less

5-Amino-4,6-dichloropyrimidine Chemical Properties

Melting point:
145-148 °C (lit.)
Boiling point:
270.44°C (rough estimate)
Density 
1.6662 (rough estimate)
refractive index 
1.6300 (estimate)
storage temp. 
2-8°C
solubility 
slightly soluble
form 
Crystals or Powder
pka
-3.01±0.26(Predicted)
color 
Yellow-brown
Water Solubility 
slightly soluble
Sensitive 
Moisture Sensitive
BRN 
126885
InChIKey
NIGDWBHWHVHOAD-UHFFFAOYSA-N
CAS DataBase Reference
5413-85-4(CAS DataBase Reference)
NIST Chemistry Reference
5-Amino-4,6-dichloropyrimidine(5413-85-4)
EPA Substance Registry System
5-Pyrimidinamine, 4,6-dichloro- (5413-85-4)
More
Less

Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
10-21
TSCA 
Yes
HS Code 
29335995

MSDS

More
Less

5-Amino-4,6-dichloropyrimidine Usage And Synthesis

Chemical Properties

Yellowish-brown crystals or powder

Uses

An intermediate in the production of many biological inhibitors.

Uses

5-Amino-4,6-dichloropyrimidine was used in the synthesis of:

  • oxepane ring containing monocyclic, conformationally restricted bicyclic and spirocyclic nucleosides
  • conformationally locked bicyclo[2.2.1]heptane/oxa-bicyclo[3.2.1]octane nucleosides
  • N(7)-substituted purines
  • chiral derivatives of (+)-erythro-9-(2-hydroxy-3-nonyl)adenine
  • 9-alkyl-6-substituted-purine analogs, potent anticonvulsant agents
  • pyrimido-oxazepines in a three-step process with microwave heating at 150°C

5-Amino-4,6-dichloropyrimidineSupplier

Liyang Kunlu biological technology co.,ltd Gold
Tel
0519-87310015 13813530041
Email
200601296@qq.com
Suzhou Tianhong Medicine Chemical Technology Co.,Ltd. Gold
Tel
18949937116
Email
dongye.huaxue@126.com
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Email
nbcxkj@126.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com