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ChemicalBook >  Product Catalog >  Natural Products >  Alkaloids >  (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester

(2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester

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(2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester Basic information

Product Name:
(2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester
Synonyms:
  • (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester
  • Demethoxyvindoline
  • Vindolidin
  • Vindolidine
  • Vindorosin
  • Vindorosine
  • 4-acetoxy-3-hydroxy-1-methyl-6,7-didehydro-aspidospermidine-3-carboxylic acid methyl ester
  • Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-
CAS:
5231-60-7
MF:
C24H30N2O5
MW:
426.51
Product Categories:
  • Alkaloids
Mol File:
5231-60-7.mol
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(2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester Chemical Properties

Melting point:
167°
alpha 
D16 -31° (chloroform)
Boiling point:
532.8±50.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
pka
11.49±0.60(Predicted)
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(2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester Usage And Synthesis

Description

An imidazolidinocarbazole alkaloid present in Vinca rosea L., the base is best crystallized from a mixture of C6H6 and light petroleum. It yields colourless needles and has [α]16D - 31 ° (CHCl3). The ultraviolet spectrum consists of two absorption maxima occurring at 250 and 302 mμ.

References

Moza, Trojanek., Chern. & Ind., 1425 (1962) Moza, Trojanek., Collect. Czech. Chern. Cornrnun., 28, 1419, 1427 (1963) Synthesis: Buchi, Matsumoto, Nishimura.']. A mer. Chern. Soc., 93, 3299 (1971)

(2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl esterSupplier

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