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FMOC-LYS(ME)2-OH HCL

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FMOC-LYS(ME)2-OH HCL Basic information

Product Name:
FMOC-LYS(ME)2-OH HCL
Synonyms:
  • N-ALPHA-FMOC-N-EPSILON,EPSILON-DIMETHYL-L-LYSINE HYDROCHLORIDE SALT
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-DIMETHYL-L-LYSINE HYDROCHLORIDE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON,N-EPSILON-DIMETHYL-L-LYSINE HYDROCHLORIDE
  • FMOC-LYS(ME)2-OH HCL
  • FMOC-LYSINE(ME)2-OH HCL
  • FMOC-N-EPSILON-DIMETHYL-L-LYSINE HYDROCHLORIDE
  • FMOC-N-EPSILON,EPSILON-DIMETHYL-L-LYSINE HYDROCHLORIDE SALT
  • FMOC-L-LYS(ME2)-OH HCL
CAS:
252049-10-8
MF:
C23H29ClN2O4
MW:
432.95
Product Categories:
  • amino acids
  • Amino Acids & Derivatives
  • Fluorescent Labels & Indicators
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • proteins
Mol File:
252049-10-8.mol
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FMOC-LYS(ME)2-OH HCL Chemical Properties

Melting point:
>107°C (dec.)
storage temp. 
Store at +2°C to +8°C.
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Pale Yellow
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Safety Information

HazardClass 
IRRITANT
HS Code 
29225090
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FMOC-LYS(ME)2-OH HCL Usage And Synthesis

Chemical Properties

White to off white crystalline powder

Uses

Di-Me L-lysine derivative. The methylation of lysine in histone tails is a common posttranslational modification that functions in histone-regulated chromatin condensation, with binding of methylated lysine occurring in aromatic pockets on chromodomain proteins.

Definition

ChEBI: Fmoc-lys(ME)2-OH hcl is a member of fluorenes.

General Description

A novel derivative for the introduction of dimethyl-lysine during Fmoc SPPS. Ref [1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.

The product number for this product was previously 04-12-1269.

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