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CHONDROITIN SULFATE B SODIUM SALT

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CHONDROITIN SULFATE B SODIUM SALT Basic information

Product Name:
CHONDROITIN SULFATE B SODIUM SALT
Synonyms:
  • CHONDROITIN SULFATE B PORCINE
  • CHONDROITIN SULFATE B SODIUM SALT
  • CHRONDROITIN SULFATE B
  • CHRONDROITIN SULFATE B, PORCINE
  • COPOLY(BETA-GLUCURONIC ACID-[1->3]-N-ACETYL-BETA-GALACTOSAMINE-4-SULFATE-[1->4] SODIUM SALT
  • DERMATAN SULFATE
  • DERMATAN SULFATE I PORCINE
  • DERMATAN SULFATE PORCINE
CAS:
54328-33-5
MF:
NULL
MW:
1526.03
Mol File:
Mol File
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CHONDROITIN SULFATE B SODIUM SALT Chemical Properties

Melting point:
>187°C (dec.)
refractive index 
-68 ° (C=1, H2O)
storage temp. 
2-8°C
solubility 
H2O: soluble5mg/mL, clear, colorless
form 
lyophilized powder
color 
White to Off-White
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10-21
HS Code 
39139000

MSDS

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CHONDROITIN SULFATE B SODIUM SALT Usage And Synthesis

Chemical Properties

Also available: fractionated dermatan sulfates with Av. Mw 25,000 ± 2,500 and 50,000 ± 5,000 and different Anti-Xa and Anti-IIa activities. Please inquire

Uses

Antithrombotic.

Uses

Chondroitin sulfate B may be used to study its roles as a biomolecule receptor, mediator of cell signaling and cell binding molecule. It may be used to compare its properties to those of chondroitin sulfate A and chondroitin sulfate C. Chondroitin sulfate B is used to study β peptide(1-42) cytotoxicity.

Definition

ChEBI: Dermatan sulfate polyanion is the conjugate base of dermatan sulfate, obtained by deprotonation of carboxy and sulfate groups. It is a monocarboxylic acid anion, an organosulfate oxoanion and a polyanionic polymer. It is a conjugate base of a dermatan sulfate.

brand name

Orgaran (Organon).

General Description

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans. Chondroitin sulfate B (Dermatam sulfate) is a component of proteoglycans such as decorin, biglycan and versican. Chondroitin sulfate B is used to study β peptide (1-42) cytotoxicity.

Biochem/physiol Actions

As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.

Purification Methods

Dermatan sulfate is purified by digestion with papain and hyaluronidase, and fractionation using aqueous EtOH. [Gifonelli & Roden Biochemical Preparations 12 1 1968.]

CHONDROITIN SULFATE B SODIUM SALTSupplier

Hubei Baidu Chemical Co., Ltd Gold
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027-027-59223020 13627137652
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J & K SCIENTIFIC LTD.
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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Sales-CN@TCIchemicals.com