Diglycolic acid Chemical Properties

Melting point:

140-144 °C (lit.)

Boiling point:

167.16°C (rough estimate)

Density 

1.486

refractive index 

1.4000 (estimate)

storage temp. 

Sealed in dry,2-8°C

solubility 

ethanol: soluble5%, clear to slightly hazy, colorless to greenish-yellow

form 

Crystalline Powder

pka

pK1:2.96 (25°C)

color 

White to light beige

Water Solubility 

Soluble

BRN 

1072117

InChIKey

QEVGZEDELICMKH-UHFFFAOYSA-N

CAS DataBase Reference

110-99-6(CAS DataBase Reference)

NIST Chemistry Reference

Diglycolic acid(110-99-6)

EPA Substance Registry System

Acetic acid, 2,2'-oxybis- (110-99-6)

Safety Information

Hazard Codes 

Xn,C

Risk Statements 

22-36/37/38-34

Safety Statements 

26-36-45-36/37/39

RIDADR 

2811

WGK Germany 

3

RTECS 

AJ1530000

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29171900

Toxicity

LD50 orl-rat: 500 mg/kg ACIEAY 14,94,75

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Diglycolic acid Usage And Synthesis

Chemical Properties

white to light beige crystalline powder

Uses

Diglycolic acid was used in the preparation of needle-like aragonite particles from calcium nitrate aqueous solutions.

Definition

ChEBI: Diglycolic acid is a dicarboxylic acid.

General Description

Diglycolic acid is a toxic metabolite of diethylene glycol (DEG) responsible for DEG-induced proximal tubular necrosis.

Biochem/physiol Actions

Diglycolic acid has antithrombogenic properties and induces vasodilation. It inhibits succinate dehydrogenase activity in human proximal tubule cells.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating vapors.

Purification Methods

Crystallise diglycolic acid from water. [Beilstein 3 IV 577.]

Diglycolic acid(110-99-6)Related Product Information

• Diethylene glycol
• Hyaluronic acid
• Bromoacetaldehyde diethyl acetal
• Iminodiacetic acid
• 2-Butoxyethanol
• Allyl phenoxyacetate
• Monoethanolamine
• Mercaptoacetic acid
• Triclopyr
• Methyl glycolate
• Ethyl 2-(Chlorosulfonyl)acetate
• Dimethyl ether
• Fluroxypyr
• Phenoxyacetic acid
• Sodium glycolate
• 2,2-Diethoxyethylamine
• Ethyl glycolate
• Ascoric Acid