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2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE

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2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE Basic information

Product Name:
2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE
Synonyms:
  • 2-[2-(2-methoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione
  • Carvedilol Impurity 4
  • Carvedilol Impurity XA
  • Carvedilol Impurity 17
  • 2-(2-(2-Methoxyphenoxy)ethyl)isoindoline-1,3-dione
  • 1H-Isoindole-1,3(2H)-dione, 2-[2-(2-methoxyphenoxy)ethyl]-
  • 2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE
CAS:
26646-63-9
MF:
C17H15NO4
MW:
297.31
Mol File:
26646-63-9.mol
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2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE Chemical Properties

Melting point:
102-108 °C
Boiling point:
449.5±25.0 °C(Predicted)
Density 
1.278±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly), DMSO (Slightly)
form 
Solid
pka
-2.27±0.20(Predicted)
color 
White to Off-White
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2-[2-(2-METHOXY-PHENOXY)-ETHYL]-ISOINDOLE-1,3-DIONE Usage And Synthesis

Uses

N-[2-(o-Methoxyphenoxy)ethyl]phthalimide is a useful synthetic intermediate in the synthesis of Carvedilol (C184625); a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.

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