1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID Chemical Properties

Boiling point:

432.3±45.0 °C(Predicted)

Density 

1.309±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

4.46±0.20(Predicted)

form 

Solid

CAS DataBase Reference

188527-21-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

43

Safety Statements 

36/37

1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID Usage And Synthesis

Uses

1-?(Benzyloxycarbonyl)?pyrrolidine-?3-?carboxylic Acid is a reagent used in the synthesis of cyclin-dependent kinase 4-inhibitors (CDK4) for cancer treatments. Also used towards the discovery of a potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer pased upon benzimidazole carboxamide moieties.

1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID(188527-21-1)Related Product Information

• 1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID
• (S)-N-CBZ-PYRROLIDINE-2-CARBOXYLIC ACID
• 3-Pyrrolidinecarboxylic acid
• (R )-1-Cbz-pyrrolidine-3-carboxylic acid,(R)-1-N-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID
• 1-N-CBZ-4-HYDROXY-BETA-PROLINE
• TRANS-4-N-BOC-AMINO-1-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID
• PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER 3-METHYL ESTER
• TRANS-4-AMINO-1-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID
• 3-Boc-amino-1-Cbz-pyrrolidine-3-carboxylic acid
• (S)-1-Cbz-pyrrolidine-3-carboxylic acid
• 1-CBZ-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER
• R-1-CBZ-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER
• 1-Cbz-3-pyrrolidine carboxylic Acid Methyl Ester
• 4-(3-CHLORO-PHENYL)-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER
• 4-PHENYL-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER
• 4-(4-METHOXY-PHENYL)-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER
• 4-(2-CHLORO-PHENYL)-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER
• 4-(4-CHLORO-PHENYL)-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-BENZYL ESTER