5-METHOXY-2-NITROBENZONITRILE Chemical Properties

Melting point:

96 °C

Boiling point:

352.2±32.0 °C(Predicted)

Density 

1.32±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

Appearance

Light brown to yellow Solid

Safety Information

HS Code 

2926907090

5-METHOXY-2-NITROBENZONITRILE Usage And Synthesis

Synthesis

Step 2: Synthesis of 5-methoxy-2-nitrobenzonitrile To a 100 mL round bottom flask was added 5-methoxy-2-nitrobenzamide (2.1 g, 0.01 mol), trifluoroacetic anhydride (2.2 mL), triethylamine (2.9 mL) and dichloromethane (30 mL). The reaction mixture was stirred at room temperature for 1 hour. After completion of the reaction, the reaction mixture was washed with distilled water (30 mL × 2). The organic layer was separated and dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure to give 1.75 g (92% yield) of white solid product. Mass spectrometry (MS) showed m/z: 179 ([M + H]+).

References

[1] Patent: US2010/120741, 2010, A1. Location in patent: Page/Page column 59

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