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4-fluoro-7-hydroxy-1-indanone

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4-fluoro-7-hydroxy-1-indanone Basic information

Product Name:
4-fluoro-7-hydroxy-1-indanone
Synonyms:
  • 4-FLUORO-7-HYDROXY-1-INDANONE
  • 4-FLUORO-7-HYDROXYINDAN-1-ONE
  • 4-fluoro-7-hydroxy-2,3-dihydro-1H-inden-1-one
  • 4-Fluoro-2,3-dihydro-7-hydroxy-1H-inden-1-one
  • 1H-Inden-1-one, 4-fluoro-2,3-dihydro-7-hydroxy-
  • 4-FLUORO-7-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-ONE(WXC05104)
  • 4-fluoro-7-hydroxy-2,3-dihydroinden-1-one
  • 4-fluoro-
CAS:
136191-16-7
MF:
C9H7FO2
MW:
166.15
Mol File:
136191-16-7.mol
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4-fluoro-7-hydroxy-1-indanone Chemical Properties

Boiling point:
335.2±42.0 °C(Predicted)
Density 
1.412
pka
10.30±0.20(Predicted)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
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4-fluoro-7-hydroxy-1-indanone Usage And Synthesis

Uses

4-fluoro-7-hydroxy-1-indanone can be used as an intermediate in organic syntheses.

Preparation

The raw material compound was mixed with aluminum chloride and then the reaction was heated to 100 °C. After 15 minutes, heat the reactants to 180 °C. Cool the mixture to room temperature after 3 h. Add ethyl acetate to the reaction solution and stir for 2 h. The resulting organic phase is dried on anhydrous sodium sulfate and concentrated under reduced pressure. After purification, 4-fluoro-7-hydroxy-1-indanone was obtained.

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