N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Basic information
- Product Name:
- N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
- Synonyms:
-
- N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
- WAY 213613
- N4-[4-(2-Bromo-4,5-difluorophenoxy)phenyl)]-L-asparagine
- L-Asparagine, N-[4-(2-bromo-4,5-difluorophenoxy)phenyl]-
- (S)-2-amino-4-((4-(2-bromo-4,5-difluorophenoxy)phenyl)amino)-4-oxobutanoic acid
- WAY 213613,WAY213613
- CAS:
- 868359-05-1
- MF:
- C16H13BrF2N2O4
- MW:
- 415.19
- Mol File:
- 868359-05-1.mol
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N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Chemical Properties
- Boiling point:
- 565.6±50.0 °C(Predicted)
- Density
- 1.664±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at RT
- solubility
- DMSO: >10mg/mL
- form
- white powder
- pka
- 2.38±0.10(Predicted)
- color
- White to off-white
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N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Usage And Synthesis
Uses
WAY 213613 is a selective non-substrate inhibitor of EAAT2. It is used in the methods of treating or inhibiting onset of Huntington''s disease with gene modulatory compounds.
Biological Activity
Potent, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC 50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). Exhibits no activity towards ionotropic and metabotropic glutamate receptors.
storage
Desiccate at RT
N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
Shanghai Chaolan Chemical Technology Center
- Tel
- QQ:65489617 15618227136
- Sales@ATKchemical.com
Fan De(Beijing) Biotechnology Co., Ltd.
- Tel
- 15911056312
- liming@bio-fount.com
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N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE(868359-05-1)Related Product Information
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- WASP (B-9)
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- N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
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