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DMT-dC(ac) Phosphoramidite

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DMT-dC(ac) Phosphoramidite Basic information

Product Name:
DMT-dC(ac) Phosphoramidite
Synonyms:
  • (2R,3S,5R)-5-(4-ACETAMIDO-2-OXOPYRIMIDIN-1(2H)-YL)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE
  • (2R,3S,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-YL)-2-((BIS(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-YL 2-cyanoethy diisopropylphosphoramidite
  • N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-3'-[2-cyanoethyl-N,N-bis(1-methylethyl)phosphoramidite]cytidine
  • N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite
  • N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite
  • N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite
  • Ac-dC Phosphoramidite
  • (2S,3R,5S)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenl)methoxy)meth
CAS:
154110-40-4
MF:
C41H50N5O8P
MW:
771.84
EINECS:
2017-001-1
Product Categories:
  • Pharmaceutical
  • Amidite
Mol File:
154110-40-4.mol
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DMT-dC(ac) Phosphoramidite Chemical Properties

storage temp. 
-20°C
solubility 
DMSO : 100 mg/mL (129.56 mM; Need ultrasonic)
form 
powder
pka
10.26±0.20(Predicted)
color 
white to off-white
InChI
InChI=1/C41H50N5O8P/c1-28(2)46(29(3)4)55(52-25-11-23-42)54-36-26-39(45-24-22-38(43-30(5)47)44-40(45)48)53-37(36)27-51-41(31-12-9-8-10-13-31,32-14-18-34(49-6)19-15-32)33-16-20-35(50-7)21-17-33/h8-10,12-22,24,28-29,36-37,39H,11,25-27H2,1-7H3,(H,43,44,47,48)/t36-,37+,39+,55?/s3
InChIKey
MECWEBCHRKVTNV-QQIWIMIASA-N
SMILES
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(NC(C)=O)=NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,40,r|
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29349990
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DMT-dC(ac) Phosphoramidite Usage And Synthesis

Chemical Properties

White or off-white power

Uses

Ac-dC phosphoramidite is a nucleoside used in the preparation of cytidine-?based nucleotide-?lipids which can act as supramolecular gelators depending on both the nucleobase and the presence of salts.

Definition

5'-O-DMT-N4-Acetyl-2'-Deoxycytidine-CE phosphoramidite (DMT-dC(ac) Phosphoramidite) is a cytidine phosphoramidite monomer that can be applied to make oligodeoxynucleotides.

storage

-20°C, protect from light, stored under nitrogen. In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen).

DMT-dC(ac) Phosphoramidite Supplier

Hefei Huana Biomedical Technology Co.,Ltd Gold
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