Basic information Safety Supplier Related

N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE

Basic information Safety Supplier Related

N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE Basic information

Product Name:
N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE
Synonyms:
  • N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE
  • Sematilide
  • N-[2-(DIETHYLAMINO)ETHYL]-4-(METHANESULFONAMIDO)BENZAMIDE
  • N-(2-Diethylaminoethyl)-4-(methylsulfonylamino)benzamide
  • RU-752
  • N-(2-(DiethylaMino)ethyl)-4-(MethylsulfonaMido)benzaMide
  • Benzamide,N-[2-(diethylamino)ethyl]-4-[(methylsulfonyl)amino]-
  • N-(diethyl-amino-ethyl-)-4-mesyl-amino-benz-amide
CAS:
101526-83-4
MF:
C14H23N3O3S
MW:
313.42
Mol File:
101526-83-4.mol
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N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE Chemical Properties

Density 
1.205±0.06 g/cm3(Predicted)
pka
7.43±0.10(Predicted)
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N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE Usage And Synthesis

Uses

Cardiac depressant (anti-arrhythmic).

in vivo

Sematilide (0.3-1.0 mg/kg, intravenously i.v.) is effective in a canine model of arrhythmia[2].

Animal Model:Mongrel dogs of either sex (10-18 kg body weight)[2]
Dosage:0.3, 1, 3, and 10 mg/kg
Administration:I.v. infusions
Result:Demonstrated antiarrhythmic effects at 0.3 and 3.0 mg/kg.

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N-(DIETHYLAMINOETHYL)-4-METHYLSULFOAMINOBENZAMIDE(101526-83-4)Related Product Information