Basic information Safety Supplier Related

2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine

Basic information Safety Supplier Related

2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine Basic information

Product Name:
2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine
Synonyms:
  • 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine
  • MPEG9-NH2
  • m-PEG9-amine
  • Methyl-PEG9-amine
  • 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
  • mPEG9-NH2/2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine
CAS:
211859-73-3
MF:
C19H41NO9
MW:
427.53
Product Categories:
  • peg
Mol File:
211859-73-3.mol
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2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine Chemical Properties

Boiling point:
484.3±40.0 °C(Predicted)
Density 
1.060
storage temp. 
2-8°C, protect from light
form 
Liquid
pka
8.74±0.10(Predicted)
color 
Colorless to light yellow
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2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine Usage And Synthesis

Description

m-PEG9-amine is a PEG linker containing an amino group and 9 PEG units. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG9-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Cleavable Linker; PEGs

References

[1] Xuyuan Gu, et al. Oligomer-Amino Acid Conjugates. US20120053237A1.

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