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4-Amino-2-fluoro-5-methoxybenzoic acid

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4-Amino-2-fluoro-5-methoxybenzoic acid Basic information

Product Name:
4-Amino-2-fluoro-5-methoxybenzoic acid
Synonyms:
  • 4-Amino-2-fluoro-5-methoxybenzoic acid
  • Benzoic acid, 4-amino-2-fluoro-5-methoxy-
  • 4-Amino-2-fluoro-5-methoxybenzoic acid USP/EP/BP
CAS:
1001346-91-3
MF:
C8H8FNO3
MW:
185.15
Mol File:
1001346-91-3.mol
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4-Amino-2-fluoro-5-methoxybenzoic acid Chemical Properties

storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
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Safety Information

HS Code 
2922500090
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4-Amino-2-fluoro-5-methoxybenzoic acid Usage And Synthesis

Synthesis

A solution of 2-fluoro-5-methoxy- 4-nitrobenzoic acid (10 g, 46 mmol), HOAc (50 mL), and MeOH (50 mL) was hydrogenated using a hydrogen balloon overnight. The solution was then filtered through celite and concentrated to a residue, which was triturated with ether and ethyl acetate. The solid was filtered and dried to give the product 4-Amino-2-fluoro-5-methoxybenzoic acid as a light yellow powder (8.3 g, 98 %).

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