ChemicalBook > Product Catalog > API > Hormones and the Endocrine System > Pancreatic hormone and blood sugar regulation > Levemir (tn)
Levemir (tn)
Levemir (tn) Basic information
- Product Name:
- Levemir (tn)
- Synonyms:
-
- D04539
- Insulin detemir
- Insulin detemir (genetical recombination)
- Insulin detemir (genetical recombination) (jan)
- Insulin detemir (usan/inn)
- Levemir
- Levemir (tn)
- Levemir (tn) USP/EP/BP
- CAS:
- 169148-63-4
- MF:
- C267H402N64O76S6
- MW:
- 5916.82198
- Mol File:
- 169148-63-4.mol
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Levemir (tn) Chemical Properties
- form
- Liquid
- color
- Colorless to light yellow
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Levemir (tn) Usage And Synthesis
Uses
Antidiabetic.
in vivo
Insulin Detemir (d-INS) (5 IU/kg; i.p.; once daily; 2 weeks) demonstrates weight-sparing effects compared with other insulin formulations, and shows a intestinal tissues preference, potentially involving the activation of insulin/-catenin/CREB signaling pathways[1].
| Animal Model: | Obese type 2 diabetic db/db mice[1] |
| Dosage: | 5 IU/kg |
| Administration: | Intraperitoneal injection; once daily for 2 weeks |
| Result: | Decreased body weight of the mice after 14-day daily injection of d-INS (5 IU/kg) significantly compared with those injected with the same dose of human Insulin or saline. Induced rapid phosphorylation of protein kinase B (Akt) in the gut L cells of normal mice. |
Levemir (tn)Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- 021-50182298 021-50180596
- sales@boylechem.com
Beijing HuaMeiHuLiBiological Chemical
- Tel
- 010-56205725
- waley188@sohu.com
China Nobel Chem Co., Limited
- Tel
- +86(0)21 60484900
LUCKY PHARMA CO., LIMITED
- Tel
- 0571-86403260 86403970
- lucky@lkbiology.com
Shanghai Haozhixiang Biotechnology Co., Ltd
- Tel
- 526763801 13301653310
- 526763801@qq.com