Glabranin Chemical Properties

Boiling point:

545.9±50.0 °C(Predicted)

Density 

1.244±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

7.68±0.40(Predicted)

color 

White to off-white

LogP

6.020 (est)

Glabranin Usage And Synthesis

Uses

Glabranine, an flavonoid, is isolated from Tephrosia s.p, exerts a inhibitory effect in vitro on the dengue virus[1]. Glabranine forms interaction with the soluble ectodomain of DENV type 2 (DENV2) E protein[2].

Definition

ChEBI: A dihydroxyflavanone that is pinocembrin substituted by a prenyl group at position 8.

target

Antifection

References

[1] Sánchez I, et al. Antiviral effect of flavonoids on the dengue virus. Phytother Res. 2000 Mar;14(2):89-92. DOI:10.1002/(sici)1099-1573(200003)14:23.0.co;2-c
[2] Ismail NA, et al. Molecular Docking and Molecular Dynamics Simulation Studies to Predict Flavonoid Binding on the Surface of DENV2 E Protein. Interdiscip Sci. 2017 Dec;9(4):499-511. DOI:10.1007/s12539-016-0157-8

Glabranin(41983-91-9)Related Product Information

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