ChemicalBook > Product Catalog > API > Nervous system drugs > Antipsychotics > Lurasidone hydrochloride
Lurasidone hydrochloride
Lurasidone hydrochloride Basic information
- Product Name:
- Lurasidone hydrochloride
- Synonyms:
-
- Lurasidonhydrochloride
- Lurasidonhydrochlorid
- (3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride
- (3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride
- Lurasidone Hydrochloride Tablets
- Exodiene Lurasidone
- Lurasidone HCl / Lurasidone Hydrochloride
- (3aR,4R,7S,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)
- CAS:
- 367514-88-3
- MF:
- C28H37ClN4O2S
- MW:
- 529.14
- EINECS:
- 682-423-6
- Product Categories:
-
- Chiral Reagents
- Intermediates & Fine Chemicals
- Pharmaceuticals
- 367514-88-3
- API
- Mol File:
- 367514-88-3.mol
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Lurasidone hydrochloride Chemical Properties
- Melting point:
- 198-205°C
- Flash point:
- 9℃
- storage temp.
- Refrigerator
- solubility
- DMSO : 10 mg/mL (18.90 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
- form
- Powder
- color
- White to off-white
- InChI
- InChI=1/C28H36N4O2S.ClH/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26;/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2;1H/t18-,19+,20-,21-,24+,25-;/s3
- InChIKey
- PQXKDMSYBGKCJA-CVTJIBDQSA-N
- SMILES
- O=C1N(C(=O)[C@@]2([H])[C@]3([H])CC[C@@]([H])(C3)[C@@]12[H])C[C@@H]1CCCC[C@H]1CN1CCN(C2=NSC3=CC=CC=C23)CC1.Cl |&1:5,7,11,14,17,22,r|
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Safety Information
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 7-16-36/37-45
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 1
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Lurasidone hydrochloride Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively
Uses
An antipsychotic used for treatment of schizophrenia.
Definition
ChEBI: A hydrochloride obtained by reaction of lurasidone with one equivalent of hydrochloric acid. An atypical antipsychotic agent used for the treatment of schizophrenia.
Biological Activity
Lurasidone is an atypical antipsychotic, used clinically for treatment of schizophrenia and bi-polar disorder. It has nanomolar activity as an antagonist at dopamine D2, serotonin 5-HT2A, 5-HT7, and α2C-adrenergic receptors and as an agonist at 5-HT1A receptors.
Lurasidone hydrochlorideSupplier
Hefei Topway Biotechnology Co.,Ltd Gold
- Tel
- 0551-65326752 14755135869
- xxhasym@163.com
Jinan Jianfeng Chemical Co., Ltd. Gold
- Tel
- 0531-88110457; 18954159893
- demi@pharmachemm.com
Jinan Baozhao Pharmaceutical Technology Co., Ltd. Gold
- Tel
- 0531-82371868 13210529039
- baozhaopharm@163.com
Shandong Risen-Sun Pharmaceutical Co., Ltd Gold
- Tel
- +8615621883869 15621883869
- liutf@jewim.com.cn
Jinan Million Pharmaceutical Co., Ltd Gold
- Tel
- 0531-68659554 13031714605
- 3299907431@qq.com
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Lurasidone hydrochloride(367514-88-3)Related Product Information
- (3aR,4S,7R,7aS)-2-{(1R,2S)-2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-ylMethyl]cyclohexylMethyl}hexahydro-4,7-Methano-2H-isoindole-1,3-dione hydrochloride
- Lurasidon hydrochloride iMpurity
- Nsc237999
- MDYJLJKDGQUHSJ-HTWOXQOSSA-N
- VILAZODONE
- Aprepitant
- ETOFIBRATE
- Posaconazole
- Defactinib
- MK-2206 2HCl
- PHA-665752
- Imatinib mesylate
- Tozasertib
- Veliparib
- MAVBUKOHERNHBQ-UHFFFAOYSA-N
- s,s-endo-lurasidone HCl
- 3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]-1,2-benzothiazole
- Lurasidone Amine Impurity