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Amlodipine Dimethyl Ester

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Amlodipine Dimethyl Ester Basic information

Product Name:
Amlodipine Dimethyl Ester
Synonyms:
  • Amlodipine Dimethyl Ester
  • AMlodipine IMpurity F (DiMethyl IMpurity)
  • 2-[(2-AMinoethoxy)Methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-Methyl-3,5-pyridinedicarboxylic Acid 3,5-diMethyl Ester
  • 3-Methyl 5-Methyl 4-(2-Chlorophenyl)-6-Methyl-2-[[2- [(2-aMinoethoxy)Methyl]-1,4-dihydropyridine-3,5-dicarboxylat
  • diMethyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • AMlodipine IMpurity F(EP)
  • AMlodipine EP IMpurity F
  • 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester
CAS:
140171-66-0
MF:
C19H23ClN2O5
MW:
394.85
Product Categories:
  • Aromatics
  • Heterocycles
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
140171-66-0.mol
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Amlodipine Dimethyl Ester Chemical Properties

Melting point:
42-45°C
Boiling point:
516.6±50.0 °C(Predicted)
Density 
1.247±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, Refrigerator, Under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
8.97±0.10(Predicted)
color 
Pale Yellow to Yellow
Stability:
Hygroscopic
InChI
1S/C19H23ClN2O5/c1-11-15(18(23)25-2)16(12-6-4-5-7-13(12)20)17(19(24)26-3)14(22-11)10-27-9-8-21/h4-7,16,22H,8-10,21H2,1-3H3
InChIKey
UDSAEMGNQXMCDF-UHFFFAOYSA-N
SMILES
Clc1c(cccc1)C2C(=C(NC(=C2C(=O)OC)C)COCCN)C(=O)OC
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Safety Information

WGK Germany 
WGK 3
Storage Class
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
STOT RE 2
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Amlodipine Dimethyl Ester Usage And Synthesis

Uses

Amlodipine Besilate (A633500) impurity.

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