4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride Chemical Properties

Melting point:

177-179 °C

storage temp. 

= -70C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

White solid

color 

Pale to Light Brown

4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride Usage And Synthesis

Uses

Glucocorticoid receptor activator 1 (compound A) is a phenyl aziridine precursor and an activator of the glucocorticoid receptor (GR). Glucocorticoid receptor activator 1 down-modulates TNF-induced pro-inflammatory gene expression by activating GR and can be utilized in inflammation research[1].

References

[1] De Bosscher K, et al. A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15827-32. DOI:10.1073/pnas.0505554102

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