((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Chemical Properties

Melting point:

133℃

Boiling point:

458.6±34.0 °C(Predicted)

Density 

1.33

storage temp. 

2-8°C

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Usage And Synthesis

Uses

neuromuscular blocking agent

Uses

(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic Acid γ-Lactone 3,5-Dibenzoate is a reactant used in the synthesis of 1''-C-cyano-2''-fluoro-2''-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.

Application

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate is an impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir.

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate(874638-80-9)Related Product Information

• D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester
• Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI)
• Sofosbuvir Impurity 17
• L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester
• (3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one
• N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
• L-Alanine isopropyl ester hydrochloride
• (2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate
• PSI-6130 derivative
• D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester
• 2'-deoxy-2'-fluoro-2'-C-methyluridine
• Sofosbuvir
• alpha-D-erythro-Pentofuranous-2-ulose 1,3,5-tribenzoate
• sofosBuvir impurity 36
• SofosBuvir Impurity 55
• Sofosbuvir impurity E
• SofosBuvir Impurity 40
• SofosBuvir Impurity 54