Murraol
Murraol Basic information
- Product Name:
- Murraol
- Synonyms:
-
- Polycyclic alcohol
- Murraol
- 2H-1-Benzopyran-2-one,8-[(1E)-3-hydroxy-3-methyl-1-buten-1-yl]-7-methoxy-
- 8-[(1E)-3-Hydroxy-3-methyl-1-buten-1-yl]-7-methoxy-2H-chromen-2-one
- Murraol?CAS?No.：
- CAS:
- 109741-38-0
- MF:
- C15H16O4
- MW:
- 260.29
- Mol File:
- 109741-38-0.mol
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Murraol Chemical Properties
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Cryst.
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Murraol Usage And Synthesis
Description
Murraol shows the significant proliferative activities on osteoblast-like UMR106 cells lines at the concentration of 1 × 10-10 mol/L. Murraol and auraptenol show 63 ug/mL MIC value against Klebsiella pneumoniae ATCC 4352 and Bacillus subtilis ATCC 937
Uses
Murraol (CM-c2), a coumarin, can be isolated from the leaves of Madagascar pine cork (Apiaceae). Murraol has cyclooxygenase (COX) and lipoxygenase inhibitory properties and has an inhibitory effect on the growth of cancer cells[1].
References
[1] Riviere C, et al. Antiproliferative effects of isopentenylated coumarins isolated from Phellolophium madagascariense Baker. Nat Prod Res. 2006 Aug;20(10):909-16. DOI:10.1080/14786410500277787
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