rac-trans-Ketoconazole Chemical Properties

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Low-Melting Solid

color 

White to Off-White

Safety Information

HS Code 

29349990

rac-trans-Ketoconazole Usage And Synthesis

Uses

rac-trans-Ketoconazole (Ketoconazole EP Impurity C) is a Ketoconazole (K186000) analog. The trans isomer of Ketoconazole.

Definition

ChEBI: (2R,4R)-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine is a 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine in which the dioxolane ring has R configuration at positions 2 and 4. It is an enantiomer of a (2S,4S)-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine.

rac-trans-Ketoconazole(83374-59-8)Related Product Information

• KETOCONAZOLE INTERMEDIATE
• Ketoconazole Impurity 3
• Ketoconazole Impurity 6
• 2,2,2-trideuterio-1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
• KetoconazoleN-Oxide
• Ketoconazole Impurity 9 (Ketoconazole Hydroxymethyl Impurity)
• Ketoconazole Impurity 4
• Ketoconazole Impurity 1
• Ketoconazole Impurity 15
• Ketoconazole
• cis-1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
• 2,3-Dehydro Ketoconazole
• N-Acetylpiperazine-N'-(4-phenol) Ketoconazole
• cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate
• 4-(1-Acetylpiperazin-4-yl)phenol
• 2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL
• 2',4'-Dichloroacetophenone
• Ketoconazole Impurity 2