2-Amino-5-methyl-3-thiophenecarbonitrile Chemical Properties

Melting point:

101-103°C

Boiling point:

318.5±42.0 °C(Predicted)

Density 

1.26±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

soluble in Methanol

form 

powder to crystal

pka

0.16±0.10(Predicted)

color 

Light yellow to Brown

InChIKey

YGXADLPRHBRTPG-UHFFFAOYSA-N

CAS DataBase Reference

138564-58-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

20/21/22-22

Safety Statements 

22-36/37/39

RIDADR 

3276

HazardClass 

IRRITANT

HS Code 

29349990

2-Amino-5-methyl-3-thiophenecarbonitrile Usage And Synthesis

Uses

An Impurity generated in the preparation of Olanzapine (O253750).

2-Amino-5-methyl-3-thiophenecarbonitrile(138564-58-6)Related Product Information

• Olanzapine Impurity K
• Olanzapine dimer
• 5-Methyl-2-[(2-nitrophenyl)amino]thiophene-3-carbonitrile
• Olanzapine ThioacetoxyMethylidene IMpurity Discontinued
• Olanzapine Impurity(ADP-2b)
• 4-Amino-2-methyl-10H-thiene[2,3-b][1,5]benzodiazepine hydrochloride
• IMp. A (EP): 5-Methyl-2-[(2-nitrophenyl)-aMino]thiophene-3-carbonitrile
• HydroxyMethylidene thione
• Olanzapine Benzoate
• Olanzapine Impurity(ADP-2c)
• 1-Fluoro-2-nitrobenzene
• 2-(1,2-PhenylenediaMino)-5-Methylthiphene-3-carbonitrile
• Olanzapine iMpurity (1-(5'-Methylthiophen-2'-yl)-1,3-dihydrobenzoiMidazol-2-one)
• 2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBONITRILE
• 2-AMINO-6-METHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBONITRILE
• 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBONITRILE
• Methyl 5-amino-4-cyano-3-methylthiophene-2-carboxylate
• 6-(DIMETHOXYMETHYL)-2-MERCAPTONICOTINONITRILE