Arterolane Chemical Properties

Melting point:

160-162℃

Boiling point:

572.2±45.0 °C(Predicted)

Density 

1.20

storage temp. 

Store at -20°C, protect from light, stored under nitrogen

solubility 

DMSO: soluble

form 

A solid

pka

16.70±0.46(Predicted)

color 

White to off-white

Arterolane Usage And Synthesis

Definition

ChEBI: Arterolane is an oxaspiro compound that is dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.1(3,7)]decane] substituted by a 2-[(2-amino-2-methylpropyl)amino]-2-oxoethyl group at position 4s. Its maleic acid salt is used as an antimalarial drug in combination with piperaquine. It has a role as an antimalarial and an antiplasmodial drug. It is a member of adamantanes, a secondary carboxamide, a primary amino compound, a trioxolane and an oxaspiro compound. It is a conjugate base of an arterolane(1+).

Arterolane(664338-39-0)Related Product Information

• Artemifone
• Artemisinin
• Artesunate
• Arterolane-d6