N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Chemical Properties

Melting point:

>140°C (dec.)

Density 

1.347 at 20℃

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

LogP

-1.36 at 23℃ and pH6

CAS DataBase Reference

76820-34-3(CAS DataBase Reference)

Safety Information

HS Code 

2924296000

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide Usage And Synthesis

Description

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is a non-ionic organic compound that can be used as a reaction intermediate for the preparation of amidated iodinated x-ray contrast media. The amidation reaction is typically carried out in aqueous solution with an acid catalyst at room temperature for up to 24 hours. The amidation reaction condition and time can be optimized depending on the desired end product. Industrial preparation of iohexol typically involves the use of an x-ray generator and iopamidol, which is synthesized from diethylene triamine and ethylenediamine.

Chemical Properties

White to Off-White Solid.

Uses

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is used in the preparation of X-ray contrast agents.

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide(76820-34-3)Related Product Information

• Azodicarbonamide
• PHTHALAMIDE
• N,N-Dimethylformamide
• Lauramidopropyl betaine
• N-Isopropylacrylamide
• POLY(N-ISOPROPYL ACRYLAMIDE)
• Cocamidopropyl betaine
• NITROGEN DIOXIDE
• 4-IODO-3-NITROTOLUENE
• 5-Amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
• 1-Iodo-4-nitrobenzene
• 5-Amino-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
• 2-IODO-5-NITROTOLUENE
• 2-Iodo-1-methyl-3-nitro-benzene
• ISOPHTHALAMIDE
• Iohexol
• 4-iodo-3-nitrobenzamide
• N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide